BIOL 555 Rational Drug Design
RATIONAL DRUG DESIGN
This course is designed to explore the process of structure- and ligand-based drug design, as well as the traditional trial-and-error testing methods. Subject areas include design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antiviral and anticancer agents. The use of gene technology in pharmaceutical and biotechnological research, computer modeling techniques and combinatorial approaches are also included. Original research publications will be used as case studies to illustrate the practical application of the rational drug discovery.